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Literature summary for 2.8.2.4 extracted from

  • Rizner, T.L.
    The important roles of steroid sulfatase and sulfotransferases in gynecological diseases (2016), Front. Pharmacol., 7, 30.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.8.2.4

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00011
-
 estrone pH and temperature not specified in the publication Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35000
-
 x * 35000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + estrone Homo sapiens
-
 adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P49888
-
-

Source Tissue

Source Tissue Comment Organism Textmining
placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + estrone
-
 Homo sapiens adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
 ?

Subunits

Subunits Comment Organism
? x * 35000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
SULT1E1
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the enzyme expression is downregulated in ovarian cancer up
Homo sapiens there are significantly higher mRNA levels in ectopic endometrium of deep infiltrating endometriosis, when compared to the normal endometrium. The enzyme expression is upregulated in endometrial cancer up