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Literature summary for 2.8.2.4 extracted from

  • Kapoor, R.; Sheng, J.J.
    Transfection of human prostate cancer CA-HPV-10 cells with cytosolic sulfotransferase SULT1E1 affects estrogen signaling and gene transcription (2008), Drug Metab. Dispos., 36, 316-321.
    View publication on PubMed
Search for more literature for 2.8.2.4

Cloned(Commentary)

Cloned (Comment) Organism
expression of SULT1E1 in prostate cancer CAHPV-10 cells leading to changes in the transcriptional expression of selected signal transduction-related genes, real-time RT-PCR expression analysis, overview Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information SULT1E1 transfection in CA-HPV-10 cells leads to decreased mRNA expression levels of TFRC, a cell membrane transferrin receptor gene, and increased TMEPAI mRNA levels, a gene encoding a steroid-dependent mRNA product. The estrogen-induced estrogen response element activation in CA-HPV-10 cells is repressed by SULT1E1 expression Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + 17beta-estradiol Homo sapiens
-
 adenosine 3',5'-bisphosphate + 17beta-estradiol 3-sulfate
-
 ?
additional information Homo sapiens SULT1E1 plays a regulatory role in estrogen signaling activities in human reproductive cells, including the prostate cells. SULT1E1 may function as a transcriptional mediator in transfected human prostate cancer CA-HPV-10 cells, molecular mechanism, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
CA-HPV-10 cell
-
 Homo sapiens
-
prostate cancer cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + 17beta-estradiol
-
 Homo sapiens adenosine 3',5'-bisphosphate + 17beta-estradiol 3-sulfate
-
 ?
additional information SULT1E1 plays a regulatory role in estrogen signaling activities in human reproductive cells, including the prostate cells. SULT1E1 may function as a transcriptional mediator in transfected human prostate cancer CA-HPV-10 cells, molecular mechanism, overview Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
sulfotransferase
-
 Homo sapiens
SULT1E1
-
 Homo sapiens