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Literature summary for 2.8.2.4 extracted from

  • Hirata, H.; Hinoda, Y.; Okayama, N.; Suehiro, Y.; Kawamoto, K.; Kikuno, N.; Rabban, J.T.; Chen, L.M.; Dahiya, R.
    CYP1A1, SULT1A1, and SULT1E1 polymorphisms are risk factors for endometrial cancer susceptibility (2008), Cancer, 112, 1964-1973.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
SULT1E1 expression analysis Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information SULT1E1 polymorphisms are risk factors for endometrial cancer susceptibility, genotyping and phenotyping, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + 17beta-estradiol Homo sapiens
-
adenosine 3',5'-bisphosphate + 17beta-estradiol 3-sulfate
-
?
3'-phosphoadenylyl sulfate + 2-methyl-17beta-estradiol Homo sapiens
-
adenosine 3',5'-bisphosphate + 2-methyl-17beta-estradiol 3-sulfate
-
?
3'-phosphoadenylyl sulfate + estrone Homo sapiens
-
adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
?
additional information Homo sapiens SULT1E1 catalyzes the sulfate conjugation of estrone, estradiol, catecholestrogens, and 2-methyl-estradiol. SULT1E1 polymorphisms, together with other SULT enzyme polymorphisms, are risk factors for endometrial cancer susceptibility ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
uterine endometrium
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + 17beta-estradiol
-
Homo sapiens adenosine 3',5'-bisphosphate + 17beta-estradiol 3-sulfate
-
?
3'-phosphoadenylyl sulfate + 2-methyl-17beta-estradiol
-
Homo sapiens adenosine 3',5'-bisphosphate + 2-methyl-17beta-estradiol 3-sulfate
-
?
3'-phosphoadenylyl sulfate + estrone
-
Homo sapiens adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
?
additional information SULT1E1 catalyzes the sulfate conjugation of estrone, estradiol, catecholestrogens, and 2-methyl-estradiol. SULT1E1 polymorphisms, together with other SULT enzyme polymorphisms, are risk factors for endometrial cancer susceptibility Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
SULT1E1
-
Homo sapiens