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Literature summary for 2.8.2.4 extracted from

  • Rozhin, J.; Soderstrom, R.L.; Brooks, S.C.
    Specificity studies on bovine adrenal estrogen sulfotransferase (1974), J. Biol. Chem., 249, 2079-2087.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylylsulfate + estrone Bos taurus
-
adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
r

Organism

Organism UniProt Comment Textmining
Bos taurus
-
bovine
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylylsulfate + 1,3,5(10)-estratrien-3,16alpha,17beta-triol
-
Bos taurus adenosine 3',5'-bisphosphate + 1,3,5(10)-estratrien-16alpha,17beta-diol 3-sulfate
-
r
3'-phosphoadenylylsulfate + 1,3,5(10)-estratrien-3,17alpha-diol
-
Bos taurus adenosine 3',5'-bisphosphate + 1,3,5(10)-estratrien 17alpha-ol-3-sulfate
-
r
3'-phosphoadenylylsulfate + 1,3,5(10)-estratrien-3,17beta-diol-17-monoacetate
-
Bos taurus adenosine 3',5'-bisphosphate + ?
-
r
3'-phosphoadenylylsulfate + 1,3,5(10)-estratrien-3,17beta-diol-17-monoglucosiduronate very low sulfation rate Bos taurus adenosine 3',5'-bisphosphate + ?
-
r
3'-phosphoadenylylsulfate + 1,3,5(10)-estratrien-3,17beta-diol-17-monovalerinate
-
Bos taurus adenosine 3',5'-bisphosphate + ?
-
r
3'-phosphoadenylylsulfate + 1,3,5(10)-estratrien-3-ol
-
Bos taurus adenosine 3',5'-bisphosphate + 1,3,5(10)-estratrien 3-sulfate
-
r
3'-phosphoadenylylsulfate + 11-hydroxy-1,3,5(10)-estratrien-17-one
-
Bos taurus adenosine 3',5'-bisphosphate + ?
-
r
3'-phosphoadenylylsulfate + 16-epiestriol 1,3,5(10)estratiene-3,16beta,17beta-triol Bos taurus adenosine 3',5'-bisphosphate + 16-epiestriol 3-sulfate
-
r
3'-phosphoadenylylsulfate + 17alpha-ethynyl-1,3,5(10)-estratrien-3,17beta-diol
-
Bos taurus adenosine 3',5'-bisphosphate + 17alpha-ethynyl-1,3,5(10)-estratrien-17beta-ol 3-sulfate
-
r
3'-phosphoadenylylsulfate + 3,16alpha-dihydroxy-1,3,5(10)-estratrien-17-one
-
Bos taurus adenosine 3',5'-bisphosphate + 16-alpha-hydroxy-1,3,5(10)-estratrien-17-one 3-sulfate
-
r
3'-phosphoadenylylsulfate + 3,17beta-dihydroxy-1,3,5(10),9-estratetraen-12-one
-
Bos taurus adenosine 3',5'-bisphosphate + ?
-
r
3'-phosphoadenylylsulfate + 3,17beta-dihydroxy-1,3,5(10)-estratrien-6-one high sulfation rate Bos taurus adenosine 3',5'-bisphosphate + ?
-
r
3'-phosphoadenylylsulfate + 3-hydroxy-1,3,5(10),6,8-estrapentaen-17-one
-
Bos taurus adenosine 3',5'-bisphosphate + 1,3,5(10),6,8-estrapentaen-17-one 3-sulfate
-
r
3'-phosphoadenylylsulfate + 3-hydroxy-1,3,5(10),6-estratetraen-17-one
-
Bos taurus adenosine 3',5'-bisphosphate + 1,3,5(10),6-estratetraen-17-one 3-sulfate
-
r
3'-phosphoadenylylsulfate + 3-hydroxy-1,3,5(10),7-estratetraen-17-one
-
Bos taurus adenosine 3',5'-bisphosphate + ?
-
r
3'-phosphoadenylylsulfate + 3-hydroxy-1,3,5(10),9-estratetraen-12,17-dione
-
Bos taurus adenosine 3',5'-bisphosphate + 1,3,5(10),9-estratetraen-12,17-dione 3-sulfate
-
r
3'-phosphoadenylylsulfate + 3-hydroxy-1,3,5(10)-estratrien-16-one
-
Bos taurus adenosine 3',5'-bisphosphate + 1,3,5(10)-estratriene-16-one 3-sulfate
-
r
3'-phosphoadenylylsulfate + 4-nitro-1,3,5(10)estratrien-3,17beta-diol
-
Bos taurus adenosine 3',5'-bisphosphate + ?
-
r
3'-phosphoadenylylsulfate + 7alpha-methyl-1,3,5(10)-estratrien-3,17beta-diol
-
Bos taurus adenosine 3',5'-bisphosphate + 7alpha-methyl-1,3,5(10)-estratrien 3-sulfate
-
r
3'-phosphoadenylylsulfate + 7alpha-methyl-3-hydroxy-1,3,5(10)-estratrien-17-one
-
Bos taurus adenosine 3',5'-bisphosphate + ?
-
r
3'-phosphoadenylylsulfate + estrone
-
Bos taurus adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
r
additional information enzyme does not sulfate an OH in position 2 or 4 of estrogens but sulfates, with decreased efficiency, the phenolic-OH on 6-benzoyl-naphthol, anthraquinone, fluorenes, diphenyl and tetraline, almost no sulfation of 4-hydroxybenzoic acid esters Bos taurus ?
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.1
-
-
Bos taurus