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Literature summary for 2.8.2.3 extracted from

  • Senggunprai, L.; Yoshinari, K.; Yamazoe, Y.
    Inhibitory effects of kynurenic acid, a tryptophan metabolite, and its derivatives on cytosolic sulfotransferases (2009), Biochem. J., 422, 455-462.
    View publication on PubMed
Search for more literature for 2.8.2.3

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
5,7-dichlorokynurenic acid
-
 Mus musculus
gavestinel i.e. 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl]-1H-indole-2-carboxylic acid sodium salt Mus musculus
Kynurenic acid
-
 Mus musculus
L689,560 i.e. trans-2-carboxy-5,7-dichloro-4-phenylaminocarboxylamino-1,2,3,4-tetrahydroquinoline Mus musculus
L701,324 i.e. 7-chloro-4-hydroxy-3(3-phenoxy)phenyl-2(H)-quinolinone Mus musculus
Mefenamic acid
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + 1-naphthol Mus musculus
-
 adenosine 3',5'-bisphosphate + 1-naphthyl sulfate
-
 ?
3'-phosphoadenylyl sulfate + 3,4-dihydroxyphenylacetic acid Mus musculus
-
 adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylyl sulfate + 4-nitrophenol Mus musculus
-
 adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
 ?
3'-phosphoadenylyl sulfate + beta-estradiol Mus musculus
-
 adenosine 3',5'-bisphosphate + beta-estradiol 3-sulfate
-
 ?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone Mus musculus
-
 adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylyl sulfate + desipramine Mus musculus
-
 adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylyl sulfate + L-triiodothyronine Mus musculus
-
 adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylyl sulfate + xanthurenic acid Mus musculus
-
 adenosine 3',5'-bisphosphate + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA agarose column chromatography Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + 1-naphthol
-
 Mus musculus adenosine 3',5'-bisphosphate + 1-naphthyl sulfate
-
 ?
3'-phosphoadenylyl sulfate + 3,4-dihydroxyphenylacetic acid
-
 Mus musculus adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylyl sulfate + 4-nitrophenol
-
 Mus musculus adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
 ?
3'-phosphoadenylyl sulfate + beta-estradiol
-
 Mus musculus adenosine 3',5'-bisphosphate + beta-estradiol 3-sulfate
-
 ?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
-
 Mus musculus adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylyl sulfate + desipramine
-
 Mus musculus adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylyl sulfate + L-triiodothyronine
-
 Mus musculus adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylyl sulfate + xanthurenic acid
-
 Mus musculus adenosine 3',5'-bisphosphate + ?
-
 ?

Synonyms

Synonyms Comment Organism
cytosolic sulfotransferase
-
 Mus musculus
SULT3A1 isoform Mus musculus