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Literature summary for 2.8.2.2 extracted from

  • Reich, O.; Singer, C.; Hudelist, G.; Regauer, S.
    Estrogen sulfotransferase expression in endometrial stromal sarcomas: an immunohistochemical study (2007), Pathol. Res. Pract., 203, 85-87.
    View publication on PubMed
Search for more literature for 2.8.2.2

Application

Application Comment Organism
diagnostics EST expression is a prognostic factor in breast cancer Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens EST is an enzyme that seems to play an important role in the growth of hormone-dependent tumors of the breast, prostate, and endometrium, EST expression is downregulated in endometrial stromal sarcomas, ESS. If the enzyme EST is missing in ESS, it is possible that the intratumoral levels of bio-active estrogen are high, and ESS tumor growth and progression are to be expected, overview ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
prostate
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 Homo sapiens
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sarcoma cell endometrial stromal, from 29 patients, reduced or no expression of EST Homo sapiens
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uterine endometrium
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 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information EST is an enzyme that seems to play an important role in the growth of hormone-dependent tumors of the breast, prostate, and endometrium, EST expression is downregulated in endometrial stromal sarcomas, ESS. If the enzyme EST is missing in ESS, it is possible that the intratumoral levels of bio-active estrogen are high, and ESS tumor growth and progression are to be expected, overview Homo sapiens ?
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 ?

Synonyms

Synonyms Comment Organism
EST
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 Homo sapiens
estrogen sulfotransferase
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 Homo sapiens