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Literature summary for 2.8.2.2 extracted from
- Immunohistochemical analysis of a novel dehydroepiandrosterone sulfotransferase-like protein in Drosophila neural circuits (2008), Biochem. Biophys. Res. Commun., 367, 14-20.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression analysis in brain enzyme extracts | Drosophila melanogaster |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| axon | - |
Drosophila melanogaster | 30424 | - |
| cytosol | - |
Drosophila melanogaster | 5829 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylyl sulfate + dehydroepiandrosterone | Drosophila melanogaster | - |
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
? |  |
| additional information | Drosophila melanogaster | sulfotransferase-catalyzed sulfation plays an important role in various neuronal functions such as homeostasis of catecholamine neurotransmitters and hormones | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Drosophila melanogaster | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| native enzyme partially from brain by native PAGE | Drosophila melanogaster |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | enzyme localization in neural fibers, posterior region, and dorsal part of the brain, overview | Drosophila melanogaster | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0000577 | - |
partially purified enzyme | Drosophila melanogaster |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylyl sulfate + dehydroepiandrosterone | - |
Drosophila melanogaster | adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
? | |
| additional information | sulfotransferase-catalyzed sulfation plays an important role in various neuronal functions such as homeostasis of catecholamine neurotransmitters and hormones | Drosophila melanogaster | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| dehydroepiandrosterone ST-like protein | - |
Drosophila melanogaster |
| dehydroepiandrosterone sulfotransferase | - |
Drosophila melanogaster |
| DHEA ST | - |
Drosophila melanogaster |
| DHEA ST-like protein | - |
Drosophila melanogaster |
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Release 2023.1 (January 2023)
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