Literature summary for 2.8.2.16 extracted from

Schmidt, A.; Christen, U.
A PAPS-dependent sulfotransferase in Cyanophora paradoxa inhibited by 5'-AMP, 5'-ADP, and APS (1979), Z. Naturforsch. C, 34c, 222-228.

No PubMed abstract available

Search for more literature for 2.8.2.16

Inhibitors

Inhibitors	Comment	Organism	Structure
2',5'-ADP	no inhibition	Cyanophora paradoxa
3',5'-ADP	no inhibition	Cyanophora paradoxa
5'-ADP	kinetics	Cyanophora paradoxa
5'-AMP	kinetics	Cyanophora paradoxa
adenosine 5'-phosphosulfate	i.e. APS, strong, reversible by higher PAPS-concentrations	Cyanophora paradoxa
additional information	no inhibition by 2'-AMP, 3'-AMP, cAMP	Cyanophora paradoxa

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0083	-	3'-phosphoadenylylsulfate	pH 8.5	Cyanophora paradoxa

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Na2SO4	required, activation	Cyanophora paradoxa

Organism

Organism	UniProt	Comment	Textmining
Cyanophora paradoxa	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
partial	Cyanophora paradoxa

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3'-phosphoadenylylsulfate + 2',3'-dimercaptopropanol	-	Cyanophora paradoxa	?	-	?
3'-phosphoadenylylsulfate + a thiol	-	Cyanophora paradoxa	adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate	-	?
3'-phosphoadenylylsulfate + cysteine	at about 25% the rate with dithiols	Cyanophora paradoxa	adenosine 3',5'-bisphosphate + 2-amino-3-sulfosulfanyl-propionic acid	-	?
3'-phosphoadenylylsulfate + dithioerythritol	-	Cyanophora paradoxa	?	-	?
3'-phosphoadenylylsulfate + glutathione	at about 25% the rate with dithiols	Cyanophora paradoxa	?	-	?
3'-phosphoadenylylsulfate + mercaptoethanol	at about 25% the rate with dithiols	Cyanophora paradoxa	adenosine 3',5'-bisphosphate + thiosulfuric acid S-ethylester	-	?

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
8.5	-	-	Cyanophora paradoxa

Cofactor

Cofactor	Comment	Organism	Structure
thioredoxin	activation	Cyanophora paradoxa

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.29	-	5'-ADP	pH 8.5	Cyanophora paradoxa
0.3	-	adenosine 5'-phosphosulfate	pH 8.5	Cyanophora paradoxa
0.43	-	5'-AMP	pH 8.5	Cyanophora paradoxa

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Release 2023.1 (January 2023)