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Literature summary for 2.8.2.1 extracted from

  • Seah, V.M.Y.; Wong, K.P.
    2,6-Dichloro-4-nitrophenol (DCNP), an alternate-substrate inhibitor of phenolsulfotransferase (1994), Biochem. Pharmacol., 47, 1743-1749.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2,6-Dichloro-4-nitrophenol competitive to 4-nitrophenol, 0.01 mM: 15% inhibition with substrate 4-nitrophenol, 78% inhibition with substrate dopamine Rattus norvegicus
4-nitrophenol sulfation of 2,6-dichloro-4-nitrophenol or dopamine, competitive Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Rattus norvegicus 5829
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + 2,6-dichloro-4-nitrophenol competitive to 4-nitrophenol Rattus norvegicus adenosine 3',5'-bisphosphate + 2,6-dichloro-4-nitrophenyl sulfate
-
?
3'-phosphoadenylyl sulfate + a phenol
-
Rattus norvegicus adenosine 3',5'-bisphosphate + an aryl sulfate
-
?
3'-phosphoadenylylsulfate + dopamine
-
Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
?