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Literature summary for 2.8.2.1 extracted from
- Inhibition of phenol sulfotransferase by pyridoxal phosphate (1994), Biochem. Pharmacol., 47, 2087-2095.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | 50% inhibition at 0.001 mM, excess of 2-naphthol protects | Bos taurus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylylsulfate + a phenol | Bos taurus | enzyme may be considered as detoxification enzyme which catalyzes the conjugation of xenobiotics containing a phenol group or of phenolic compounds generated by endogenous oxidation | adenosine 3',5'-bisphosphate + an aryl sulfate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| lung | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylyl sulfate + a phenol | - |
Bos taurus | adenosine 3',5'-bisphosphate + an aryl sulfate | - |
? | |
| 3'-phosphoadenylylsulfate + a phenol | enzyme may be considered as detoxification enzyme which catalyzes the conjugation of xenobiotics containing a phenol group or of phenolic compounds generated by endogenous oxidation | Bos taurus | adenosine 3',5'-bisphosphate + an aryl sulfate | - |
? | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.023 | - |
pyridoxal 5'-phosphate | - |
Bos taurus | |
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