Protein Variants | Comment | Organism |
---|---|---|
C154S | SH group titration, susceptibility to hydrogen peroxide and tetrathionate and renaturation by dithiothreitol similar to wild-type | Rattus norvegicus |
C247S | SH group titration, susceptibility to hydrogen peroxide and tetrathionate and renaturation by dithiothreitol similar to wild-type | Rattus norvegicus |
C254S | SH group titration, susceptibility to hydrogen peroxide and tetrathionate and renaturation by dithiothreitol similar to wild-type | Rattus norvegicus |
C263S | SH group titration, susceptibility to hydrogen peroxide and tetrathionate and renaturation by dithiothreitol similar to wild-type | Rattus norvegicus |
C64S | SH group titration, susceptibility to hydrogen peroxide and tetrathionate and renaturation by dithiothreitol similar to wild-type | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
hydrogen peroxide | together with stoichiometric concentration of tetrathionate, renaturation by dithiothreitol or thioredoxin. Excess molar ratio of hydrogen peroxide inactivates | Rattus norvegicus | |
iodoacetate | - |
Rattus norvegicus | |
tetrathionate | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
additional information | redox state controls enzyme activity | Rattus norvegicus |
Renatured (Comment) | Organism |
---|---|
enzyme inhibited by hydrogen peroxide together with stoichiometric concentration of tetrathionate, complete renaturation by dithiothreitol or thioredoxin | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
MST | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.12 | - |
hydrogen peroxide | pH 7.4, 0°C | Rattus norvegicus | |
0.178 | - |
tetrathionate | pH 7.4, 0°C | Rattus norvegicus |