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Literature summary for 2.8.1.11 extracted from

  • Appleyard, M.V.C.L.; Sloan, J.; Kanan, G.; Heck, I.; Kinghorn, J.; Unkles, S.
    The Aspergillus nidulans cnxF gene and its involvement in molybdopterin biosynthesis: molecular characterization and analysis of in vivo generated mutants (1998), J. Biol. Chem., 273, 14869-14876.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene cnxF, DNA and amino acid sequence determination and analysis, sequence comparison, genetic structure and organization Aspergillus nidulans

Protein Variants

Protein Variants Comment Organism
G160D radom mutagenesis, temperature-sensitive phenotype Aspergillus nidulans
G178D radom mutagenesis, temperature-sensitive phenotype Aspergillus nidulans
G342S radom mutagenesis., temperature-sensitive phenotype Aspergillus nidulans
additional information generation of several hundred cnx mutants by radom mutagenesis, activity analysis and phenotypes, overview Aspergillus nidulans

Organism

Organism UniProt Comment Textmining
Aspergillus nidulans
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gene cnxF
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Synonyms

Synonyms Comment Organism
CnxF protein
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Aspergillus nidulans
molybdopterin synthase sulfurylase
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Aspergillus nidulans

General Information

General Information Comment Organism
additional information the enzyme contains two potential nucleotide binding Gly-rich motifs (Gly-X-Gly-X-X-Gly) starting at residue positions 173 and 189 Aspergillus nidulans
physiological function te enzyme is required for the conversion of precursor Z to molybdopterin Aspergillus nidulans