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Literature summary for 2.8.1.1 extracted from

  • Picton, R.; Eggo, M.C.; Merrill, G.A.; Langman, M.J.S.; Singh, S.
    Mucosal protection against sulphide: Importance of the enzyme rhodanese (2002), Gut, 50, 201-205.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.8.1.1

Inhibitors

Inhibitors Comment Organism Structure
H2S at concentrations above 30 mM Bos taurus
H2S at concentrations above 30 mM Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
8.8
-
 H2S 20°C, pH 9.2 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
thiosulfate + cyanide Homo sapiens
-
 sulfite + thiocyanate
-
 ?
thiosulfate + cyanide Bos taurus
-
 sulfite + thiocyanate
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colon right and left Homo sapiens
-
esophagus
-
 Homo sapiens
-
rectum
-
 Homo sapiens
-
small intestine
-
 Homo sapiens
-
stomach
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.015
-
 with H2S as substrate Homo sapiens
0.047
-
 oesophagus Homo sapiens
0.128
-
 stomach Homo sapiens
0.158
-
 small intestine Homo sapiens
0.246
-
 left colon Homo sapiens
0.254
-
 rectum Homo sapiens
0.292
-
 right colon Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
H2S + cyanide
-
 Homo sapiens thiocyanate
-
 ?
H2S + cyanide
-
 Bos taurus thiocyanate
-
 ?
thiosulfate + cyanide
-
 Homo sapiens sulfite + thiocyanate
-
 ?
thiosulfate + cyanide
-
 Bos taurus sulfite + thiocyanate
-
 ?