Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
SCHNEIDER-2 cell | - |
Drosophila melanogaster | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + selenide + H2O | - |
Drosophila melanogaster | AMP + selenophosphate + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
selenophosphate synthetase 1 | - |
Drosophila melanogaster |
SPS 1 | - |
Drosophila melanogaster |
General Information | Comment | Organism |
---|---|---|
malfunction | vitamin B6 biosynthesis is significantly affected at the early stage at which megamitochondria are not formed (day 3) after isoform SPS1 knockdown. Genes related to defense and amino acid metabolism are affected at a later stage (day 5) following enzyme knockdown. Levels of pyridoxal phosphate, an active form of vitamin B6, are decreased by isoform SPS1 knockdown | Drosophila melanogaster |
metabolism | isoform selenophosphate synthetase 1 regulates vitamin B6 metabolism | Drosophila melanogaster |