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Literature summary for 2.7.9.2 extracted from

  • Niersbach, M.; Kreuzaler, F.; Geerse, R.H.; Postma, P.W.; Hirsch, H.J.
    Cloning and nucleotide sequence of the Escherichia coli K-12 ppsA gene, encoding PEP synthase (1992), Mol. Gen. Genet., 231, 332-336.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
DNA sequence determination and analysis, sequence homology with other phosphohistidine-containing enzymes, including pyruvate,phosphate dikinase from plants and Bacteroides symbiosus and Enzyme I of the bacterial PEP:carbohydrate phosphotransferase system Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
87430
-
x * 87430, calculation from nucleotide sequence Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + pyruvate + H2O Escherichia coli essential step in gluconeogenesis if pyruvate or lactate is used as carbon source AMP + phosphoenolpyruvate + phosphate
-
r

Organism

Organism UniProt Comment Textmining
Escherichia coli P23538 K-12
-
Escherichia coli P23538 gene ppsA
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + pyruvate + H2O
-
Escherichia coli AMP + phosphoenolpyruvate + phosphate
-
r
ATP + pyruvate + H2O essential step in gluconeogenesis if pyruvate or lactate is used as carbon source Escherichia coli AMP + phosphoenolpyruvate + phosphate
-
r

Subunits

Subunits Comment Organism
? x * 87430, calculation from nucleotide sequence Escherichia coli