BRENDA - Enzyme Database
show all sequences of 2.7.8.B11

Septal localization by membrane targeting sequences and a conserved sequence essential for activity at the COOH-terminus of Bacillus subtilis cardiolipin synthase

Kusaka, J.; Shuto, S.; Imai, Y.; Ishikawa, K.; Saito, T.; Natori, K.; Matsuoka, S.; Hara, H.; Matsumoto, K.; Res. Microbiol. 167, 202-214 (2016)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
a phosphatidylglycerol + a phosphatidylethanolamine
Escherichia coli
-
a cardiolipin + ethanolamine
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-
?
additional information
Escherichia coli
the enzyme homologue ClsC1 (YmdC) uses both phosphatidylethanolamine and phoshatidylglycerol as substrates for cardiolipin synthesis with the assistance of YmdB (ClsC2), the product of a neighboring gene. Enzyme homologue ClsB may also use some phospholipid other than phosphatidylglycerol
?
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Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Escherichia coli
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-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
a phosphatidylglycerol + a phosphatidylethanolamine
-
739625
Escherichia coli
a cardiolipin + ethanolamine
-
-
-
?
additional information
the enzyme homologue ClsC1 (YmdC) uses both phosphatidylethanolamine and phoshatidylglycerol as substrates for cardiolipin synthesis with the assistance of YmdB (ClsC2), the product of a neighboring gene. Enzyme homologue ClsB may also use some phospholipid other than phosphatidylglycerol
739625
Escherichia coli
?
-
-
-
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
a phosphatidylglycerol + a phosphatidylethanolamine
Escherichia coli
-
a cardiolipin + ethanolamine
-
-
?
additional information
Escherichia coli
the enzyme homologue ClsC1 (YmdC) uses both phosphatidylethanolamine and phoshatidylglycerol as substrates for cardiolipin synthesis with the assistance of YmdB (ClsC2), the product of a neighboring gene. Enzyme homologue ClsB may also use some phospholipid other than phosphatidylglycerol
?
-
-
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
a phosphatidylglycerol + a phosphatidylethanolamine
-
739625
Escherichia coli
a cardiolipin + ethanolamine
-
-
-
?
additional information
the enzyme homologue ClsC1 (YmdC) uses both phosphatidylethanolamine and phoshatidylglycerol as substrates for cardiolipin synthesis with the assistance of YmdB (ClsC2), the product of a neighboring gene. Enzyme homologue ClsB may also use some phospholipid other than phosphatidylglycerol
739625
Escherichia coli
?
-
-
-
-
Other publictions for EC 2.7.8.B11
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
739625
Kusaka
Septal localization by membran ...
Escherichia coli
Res. Microbiol.
167
202-214
2016
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728679
Tan
Discovery of a cardiolipin syn ...
Escherichia coli
Proc. Natl. Acad. Sci. USA
109
16504-16509
2012
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