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Literature summary for 2.7.8.5 extracted from
- CMP-dependent incorporation of [14C]Glycerol 3-phosphate into phosphatidylglycerol and phosphatidylglycerol phosphate by rabbit lung microsomes (1982), Biochim. Biophys. Acta, 710, 377-390.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| phosphatidylinositol | required for CMP-dependent incorporation of glycerol 3-phosphate | Oryctolagus cuniculus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Inositol | inhibits CMP-dependent incorporation of glycerol 3-phosphate by microsomes | Oryctolagus cuniculus | |
| Triton X-100 | 0.2% inhibits, lower concentrations are required for CMP-dependent incorporation of glycerol 3-phosphate | Oryctolagus cuniculus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.19 | - |
CMP | - |
Oryctolagus cuniculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Oryctolagus cuniculus | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mn2+ | required for CMP-dependent incorporation of glycerol 3-phosphate | Oryctolagus cuniculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| lung | - |
Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CMP + 1-(3-sn-phosphatidyl)-sn-glycerol 3-phosphate | - |
Oryctolagus cuniculus | CDP-diacylglycerol + sn-glycerol 3-phosphate | - |
r | |
| additional information | cytosine-beta-D-arabinofuranoside-5'-monophosphate dependent incorporation of glycerol 3-phosphate at pH 8.5 but not at pH 6.8 | Oryctolagus cuniculus | ? | - |
? | |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Oryctolagus cuniculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
- |
Oryctolagus cuniculus |
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Release 2023.1 (January 2023)
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