Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
diacylphosphatidylethanolamine + flagellar rod protein FlgG | Campylobacter jejuni | - |
? | - |
? | |
diacylphosphatidylethanolamine + flagellar rod protein FlgG | Campylobacter jejuni 81-176 | - |
? | - |
? | |
diacylphosphatidylethanolamine + lipid A | Campylobacter jejuni | - |
diacylglycerol + lipid A 1-(2-aminoethyl diphosphate) | - |
? | |
diacylphosphatidylethanolamine + lipid A | Campylobacter jejuni | - |
diacylglycerol + lipid A 4'-(2-aminoethyl diphosphate) | - |
? | |
diacylphosphatidylethanolamine + lipid A | Campylobacter jejuni 81-176 | - |
diacylglycerol + lipid A 1-(2-aminoethyl diphosphate) | - |
? | |
diacylphosphatidylethanolamine + lipid A | Campylobacter jejuni 81-176 | - |
diacylglycerol + lipid A 4'-(2-aminoethyl diphosphate) | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Campylobacter jejuni | A0A3X8T8A0 | gene cj0256 or eptC | - |
Campylobacter jejuni 81-176 | A0A3X8T8A0 | gene cj0256 or eptC | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
diacylphosphatidylethanolamine + flagellar rod protein FlgG | - |
Campylobacter jejuni | ? | - |
? | |
diacylphosphatidylethanolamine + flagellar rod protein FlgG | FlgG is modified at a single site Thr75, EptC is unable to modify other amino acids (e.g. serine and tyrosine), mass spectroscopic analysis, overview | Campylobacter jejuni | ? | - |
? | |
diacylphosphatidylethanolamine + flagellar rod protein FlgG | - |
Campylobacter jejuni 81-176 | ? | - |
? | |
diacylphosphatidylethanolamine + flagellar rod protein FlgG | FlgG is modified at a single site Thr75, EptC is unable to modify other amino acids (e.g. serine and tyrosine), mass spectroscopic analysis, overview | Campylobacter jejuni 81-176 | ? | - |
? | |
diacylphosphatidylethanolamine + lipid A | - |
Campylobacter jejuni | diacylglycerol + lipid A 1-(2-aminoethyl diphosphate) | - |
? | |
diacylphosphatidylethanolamine + lipid A | - |
Campylobacter jejuni 81-176 | diacylglycerol + lipid A 1-(2-aminoethyl diphosphate) | - |
? | |
diacylphosphatidylethanolamine + lipid A | - |
Campylobacter jejuni | diacylglycerol + lipid A 4'-(2-aminoethyl diphosphate) | - |
? | |
diacylphosphatidylethanolamine + lipid A | - |
Campylobacter jejuni 81-176 | diacylglycerol + lipid A 4'-(2-aminoethyl diphosphate) | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Cj0256 | - |
Campylobacter jejuni |
EptC | - |
Campylobacter jejuni |
pEtN transferase | - |
Campylobacter jejuni |
phosphoethanolamine transferase | - |
Campylobacter jejuni |
General Information | Comment | Organism |
---|---|---|
malfunction | the eptC-deficient Campylobacter jejuni strain shows a dramatic decrease in resistance to polymyxin B when compared with wild-type, indicating a loss of phosphoethanolamine modification of the lipid A backbone. Campylobacter strains expressing site-directed FlgG mutants show defects in motility arise directly from the loss of phophoethanolamine modification of FlgG, phenotypes, overview | Campylobacter jejuni |
physiological function | the enzyme EptC serves a dual role in modifying the flagellar rod protein, FlgG, and the lipid A domain lipooligosaccharide with a pEtN residue | Campylobacter jejuni |