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Literature summary for 2.7.8.41 extracted from

  • Houtkooper, R.H.; Akbari, H.; van Lenthe, H.; Kulik, W.; Wanders, R.J.; Frentzen, M.; Vaz, F.M.
    Identification and characterization of human cardiolipin synthase (2006), FEBS Lett., 580, 3059-3064.
    View publication on PubMed
Search for more literature for 2.7.8.41

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ the enzyme displays similar activities with Co2+, Mn2+ and Mg2+ Homo sapiens
Mg2+ the enzyme displays similar activities with Co2+, Mn2+ and Mg2+ Homo sapiens
Mn2+ the enzyme displays similar activities with Co2+, Mn2+ and Mg2+ Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9UJA2
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CDP-dimyristoylglycerol + 1,2-dioleoylphosphatidylglycerol competition experiments with [14C]-CDP-dioleoylglycerol show that the enzyme has similar activity with CDP-dimyristoylglycerol, CDP-diacylglycerol from egg yolk and CDP-dioleoylglycerol. CDP-dipalmitoylglycerol shows considerably less activity Homo sapiens 1-(1-myristoyl-2-myristoyl-sn-glycero-3-phospho)-3-(1-oleoyl-2-oleoyl-sn-glycero-3-phospho)-sn-glycerol + CMP
-
 ?
CDP-dioleoylglycerol + 1,2-dilinoleoylphosphatidylglycerol the enzyme is more active with dioleoyl and dilinoleoyl species of phosphatidylglycerol than with species with one or two palmitoyl groups Homo sapiens 1-(1-linoleoyl-2-linoleoyl-sn-glycero-3-phospho)-3-(1-oleoyl-2-oleoyl-sn-glycero-3-phospho)-sn-glycerol + CMP
-
 ?
CDP-dioleoylglycerol + 1,2-dimyristoylphosphatidylglycerol dimyristoyl phosphatidylglycerol is a very poor substrate Homo sapiens 1-(1-oleoyl-2-oleoyl-sn-glycero-3-phospho)-3-(1-myristoyl-2-oleoyl-sn-glycero-3-phospho)-sn-glycerol + CMP
-
 ?
CDP-dioleoylglycerol + 1,2-dioleoylphosphatidylglycerol the enzyme is more active with dioleoyl and dilinoleoyl species of phosphatidylglycerol than with species with one or two palmitoyl groups. Competition experiments with [14C]-CDP-dioleoylglycerol show that the enzyme has similar activity with CDP-dimyristoylglycerol, CDP-diacylglycerol from egg yolk and CDP-dioleoylglycerol. CDP-dipalmitoylglycerol shows considerably less activity Homo sapiens 1,3-bis(1,2-dioleoyl-sn-glycero-3-phospho)-sn-glycerol + CMP
-
 ?
CDP-dioleoylglycerol + 1,2-dipalmitoylphosphatidylglycerol the enzyme is more active with dioleoyl and dilinoleoyl species of phosphatidylglycerol than with species with one or two palmitoyl groups Homo sapiens 1-(1-oleoyl-2-oleoyl-sn-glycero-3-phospho)-3-(1-palmitoyl-2-palmitoyl-sn-glycero-3-phospho)-sn-glycerol + CMP
-
 ?
CDP-dioleoylglycerol + 1-oleoyl-2-linoleoyl phosphatidylglycerol the enzyme is more active with dioleoyl and dilinoleoyl species of phosphatidylglycerol than with species with one or two palmitoyl groups Homo sapiens 1-(1-oleoyl-2-oleoyl-sn-glycero-3-phospho)-3-(1-oleoyl-2-linoleoyl-sn-glycero-3-phospho)-sn-glycerol + CMP
-
 ?
CDP-dioleoylglycerol + 1-palmitoyl-2-oleoyl phosphatidylglycerol the enzyme is more active with dioleoyl and dilinoleoyl species of phosphatidylglycerol than with species with one or two palmitoyl groups Homo sapiens 1-(1-oleoyl-2-oleoyl-sn-glycero-3-phospho)-3-(1-palmitoyl-2-oleoyl-sn-glycero-3-phospho)-sn-glycerol + CMP
-
 ?
CDP-dipalmitoylglycerol + 1,2-dioleoylphosphatidylglycerol competition experiments with [14C]-CDP-dioleoylglycerol show that the enzyme has similar activity with CDP-dimyristoylglycerol, CDP-diacylglycerol from egg yolk and CDP-dioleoylglycerol. CDP-dipalmitoylglycerol shows considerably less activity Homo sapiens 1-(1-oleoyl-2-oleoyl-sn-glycero-3-phospho)-3-(1-palmitoyl-2-palmitoyl-sn-glycero-3-phospho)-sn-glycerol + CMP
-
 ?
egg yolk CDP-diacylglycerol + 1,2-dioleoylphosphatidylglycerol CDP-diacylglycerol from egg lecithin is primarily CDP-1-palmitoyl-2-oleoylglycerol. Competition experiments with [14C]-CDP-dioleoylglycerol show that the enzyme has similar activity with CDP-dimyristoylglycerol, CDP-diacylglycerol from egg yolk and CDP-dioleoylglycerol. CDP-dipalmitoylglycerol shows considerably less activity Homo sapiens a cardiolipin + CMP
-
 ?

Synonyms

Synonyms Comment Organism
C20orf155
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Homo sapiens