BRENDA - Enzyme Database show
show all sequences of 2.7.8.40

The polymerization of Aeromonas hydrophila AH-3 O-antigen LPS: concerted action of WecP and Wzy

Merino, S.; Gonzalez, V.; Tomas, J.M.; PLoS ONE 10, e0131905 (2015)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
gene wecP
Aeromonas hydrophila
Engineering
Amino acid exchange
Commentary
Organism
additional information
generation of an enzyme knockout strain Aeromonas hydrophila AH-3DELTAwecP
Aeromonas hydrophila
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
membrane
the cytosolic face of the inner membrane
Aeromonas hydrophila
16020
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate
Aeromonas hydrophila
-
UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
-
-
?
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate
Aeromonas hydrophila AH-3
-
UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Aeromonas hydrophila
B3FN88
gene wecP
-
Aeromonas hydrophila AH-3
B3FN88
gene wecP
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate
-
739417
Aeromonas hydrophila
UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
-
-
-
?
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate
-
739417
Aeromonas hydrophila AH-3
UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
-
-
-
?
Cloned(Commentary) (protein specific)
Commentary
Organism
gene wecP
Aeromonas hydrophila
Engineering (protein specific)
Amino acid exchange
Commentary
Organism
additional information
generation of an enzyme knockout strain Aeromonas hydrophila AH-3DELTAwecP
Aeromonas hydrophila
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
membrane
the cytosolic face of the inner membrane
Aeromonas hydrophila
16020
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate
Aeromonas hydrophila
-
UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
-
-
?
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate
Aeromonas hydrophila AH-3
-
UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate
-
739417
Aeromonas hydrophila
UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
-
-
-
?
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate
-
739417
Aeromonas hydrophila AH-3
UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
-
-
-
?
General Information
General Information
Commentary
Organism
malfunction
deletion of the enzyme reduces O34 antigen production in Aeromonas hydrophila strain AH-3 and reuces the survival rate of the strain. LPS profile of wild-type and mutant strains, overview
Aeromonas hydrophila
physiological function
the enzyme is involved in the synthesis of O34-antigen
Aeromonas hydrophila
General Information (protein specific)
General Information
Commentary
Organism
malfunction
deletion of the enzyme reduces O34 antigen production in Aeromonas hydrophila strain AH-3 and reuces the survival rate of the strain. LPS profile of wild-type and mutant strains, overview
Aeromonas hydrophila
physiological function
the enzyme is involved in the synthesis of O34-antigen
Aeromonas hydrophila
Other publictions for EC 2.7.8.40
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
739417
Merino
The polymerization of Aeromona ...
Aeromonas hydrophila, Aeromonas hydrophila AH-3
PLoS ONE
10
e0131905
2015
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722529
Merino
A UDP-HexNAc:polyprenol-P GalN ...
Aeromonas hydrophila, Aeromonas hydrophila AH-3
J. Bacteriol.
193
1943-1952
2011
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