BRENDA - Enzyme Database show
show all sequences of 2.7.8.30

Extracellular zinc induces phosphoethanolamine addition to Pseudomonas aeruginosa lipid A via the ColRS two-component system

Nowicki, E.M.; OBrien, J.P.; Brodbelt, J.S.; Trent, M.S.; Mol. Microbiol. 97, 166-178 (2015)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
membrane
-
Pseudomonas aeruginosa
16020
-
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Zn2+
transcription of EptA is regulated by zinc via the ColRS two-component system. ColR specifically induces phosphoethanolamine addition to lipid A in lieu of L-Ara4N when Zn2+ is present
Pseudomonas aeruginosa
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Pseudomonas aeruginosa
A0A0H2ZAB6
-
-
Pseudomonas aeruginosa UCBPP-PA14
A0A0H2ZAB6
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
diacylphosphatidylethanolamine + lipid A
-
739106
Pseudomonas aeruginosa
diacylglycerol + lipid A 4'-(2-aminoethyl diphosphate)
enzyme adds diacylphosphatidylethanolamine strictly to the lipid A 4' phosphate group
-
-
?
diacylphosphatidylethanolamine + lipid A
-
739106
Pseudomonas aeruginosa UCBPP-PA14
diacylglycerol + lipid A 4'-(2-aminoethyl diphosphate)
enzyme adds diacylphosphatidylethanolamine strictly to the lipid A 4' phosphate group
-
-
?
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
membrane
-
Pseudomonas aeruginosa
16020
-
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Zn2+
transcription of EptA is regulated by zinc via the ColRS two-component system. ColR specifically induces phosphoethanolamine addition to lipid A in lieu of L-Ara4N when Zn2+ is present
Pseudomonas aeruginosa
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
diacylphosphatidylethanolamine + lipid A
-
739106
Pseudomonas aeruginosa
diacylglycerol + lipid A 4'-(2-aminoethyl diphosphate)
enzyme adds diacylphosphatidylethanolamine strictly to the lipid A 4' phosphate group
-
-
?
diacylphosphatidylethanolamine + lipid A
-
739106
Pseudomonas aeruginosa UCBPP-PA14
diacylglycerol + lipid A 4'-(2-aminoethyl diphosphate)
enzyme adds diacylphosphatidylethanolamine strictly to the lipid A 4' phosphate group
-
-
?
Expression
Organism
Commentary
Expression
Pseudomonas aeruginosa
transcription of EptA is regulated by zinc via the ColRS two-component system. ColR specifically induces phosphoethanolamine addition to lipid A in lieu of L-Ara4N when Zn2+ is present
up
Expression (protein specific)
Organism
Commentary
Expression
Pseudomonas aeruginosa
transcription of EptA is regulated by zinc via the ColRS two-component system. ColR specifically induces phosphoethanolamine addition to lipid A in lieu of L-Ara4N when Zn2+ is present
up
Other publictions for EC 2.7.8.30
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
735018
Trombley
Phosphoethanolamine transferas ...
Haemophilus ducreyi, Haemophilus ducreyi 35000HP
PLoS ONE
10
e0124373
2015
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
739106
Nowicki
Extracellular zinc induces pho ...
Pseudomonas aeruginosa, Pseudomonas aeruginosa UCBPP-PA14
Mol. Microbiol.
97
166-178
2015
-
-
-
-
-
-
-
-
1
1
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
739495
Piek
The role of oxidoreductases in ...
Neisseria sp.
PLoS ONE
9
e106513
2014
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
734476
Wanty
The structure of the neisseria ...
Neisseria meningitidis, Neisseria meningitidis MC58
J. Mol. Biol.
425
3389-3402
2013
-
-
1
1
-
-
-
-
-
1
-
-
-
2
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-