BRENDA - Enzyme Database show
show all sequences of 2.7.8.29

Genetic evidence that phosphatidylserine synthase II catalyzes the conversion of phosphatidylethanolamine to phosphatidylserine in Chinese hamster ovary cells

Saito, K.; Nishijima, M.; Kuge, O.; J. Biol. Chem. 273, 17199-17205 (1998)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Cricetulus griseus
O08888
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
CHO-K1 cell
-
Cricetulus griseus
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
CHO-K1 cell
-
Cricetulus griseus
-
General Information
General Information
Commentary
Organism
physiological function
mutant defective in PSS II show 5% of the activity in the homogenate CHO-K1 cells and 10% of the activity in the homogenate of cells lacking PSS I, EC 2.7.8.8. The PSS II mutant grows well in medium supplemented with phosphatidylserine. However, in the medium supplemented with phosphatidylethanolamine, the PSS II-mutant is incapable of growth. In the medium with exogenous phosphatidylethanolamine, the PSS II-mutant is defective in phosphatidylserine biosynthesis
Cricetulus griseus
General Information (protein specific)
General Information
Commentary
Organism
physiological function
mutant defective in PSS II show 5% of the activity in the homogenate CHO-K1 cells and 10% of the activity in the homogenate of cells lacking PSS I, EC 2.7.8.8. The PSS II mutant grows well in medium supplemented with phosphatidylserine. However, in the medium supplemented with phosphatidylethanolamine, the PSS II-mutant is incapable of growth. In the medium with exogenous phosphatidylethanolamine, the PSS II-mutant is defective in phosphatidylserine biosynthesis
Cricetulus griseus
Other publictions for EC 2.7.8.29
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
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Cricetulus griseus
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1636
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2004
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278
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2003
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277
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717762
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Cricetulus griseus, Rattus norvegicus
J. Biol. Chem.
275
34534-34540
2000
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717208
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1999
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717761
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Control of phosphatidylserine ...
Cricetulus griseus
J. Biol. Chem.
274
23844-23849
1999
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717759
Saito
Genetic evidence that phosphat ...
Cricetulus griseus
J. Biol. Chem.
273
17199-17205
1998
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717758
Kuge
Cloning of a Chinese hamster o ...
Cricetulus griseus
J. Biol. Chem.
272
19133-19139
1997
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