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Literature summary for 2.7.8.27 extracted from
- Sphingomyelin synthase 2 is palmitoylated at the COOH-terminal tail, which is involved in its localization in plasma membranes (2009), Biochem. Biophys. Res. Commun., 381, 328-332.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| plasma membrane | - |
Homo sapiens | 5886 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ceramide + phosphatidylcholine | Homo sapiens | - |
sphingomyelin + 1,2-diacyl-sn-glycerol | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| side-chain modification | SMS2 is palmitoylated at cysteine residues via thioester bonds in the COOH-terminal cytoplasmic tail, SMS1 is not palmitoylated | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HEK-293 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ceramide + phosphatidylcholine | - |
Homo sapiens | sphingomyelin + 1,2-diacyl-sn-glycerol | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SMS1 | isoform | Homo sapiens |
| SMS2 | isoform | Homo sapiens |
| sphingomyelin synthase 2 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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