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Literature summary for 2.7.8.27 extracted from

  • Dmitrieva, V.G.; Torshina, E.V.; Yuzhakov, V.V.; Povarova, O.V.; Skvortsova, V.I.; Limborska, S.A.; Dergunova, L.V.
    Expression of sphingomyelin synthase 1 gene in rat brain focal ischemia (2008), Brain Res., 1188, 222-227.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information early response of the SMS1 gene that can be induced by both ischemia and stress Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
gene SMS1, expression analysis in healthy and ischemic neurons, effect of permanent middle cerebral artery occlusion on expression of SMS1 transcripts, overview Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Rattus norvegicus 16020
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus SMS1 is a key enzyme in the sphingomyelin cycle, metabolites of the cycle play an important role in neuronal death after ischemia, mechanism underlying cerebral ischemia, overview ?
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?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
isozyme SMS1
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Source Tissue

Source Tissue Comment Organism Textmining
brain changes in the mRNA expression of the SMS1 gene occur in rats after focal cerebral ischemia. In damaged ipsilateral cortex in the ischemic cortex, the level of SMS1 transcripts is decreased, overview Rattus norvegicus
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neuron
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Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information SMS1 is a key enzyme in the sphingomyelin cycle, metabolites of the cycle play an important role in neuronal death after ischemia, mechanism underlying cerebral ischemia, overview Rattus norvegicus ?
-
?

Synonyms

Synonyms Comment Organism
SMS1
-
Rattus norvegicus
sphingomyelin synthase 1
-
Rattus norvegicus