Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | early response of the SMS1 gene that can be induced by both ischemia and stress | Rattus norvegicus |
Cloned (Comment) | Organism |
---|---|
gene SMS1, expression analysis in healthy and ischemic neurons, effect of permanent middle cerebral artery occlusion on expression of SMS1 transcripts, overview | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Rattus norvegicus | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | SMS1 is a key enzyme in the sphingomyelin cycle, metabolites of the cycle play an important role in neuronal death after ischemia, mechanism underlying cerebral ischemia, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
isozyme SMS1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | changes in the mRNA expression of the SMS1 gene occur in rats after focal cerebral ischemia. In damaged ipsilateral cortex in the ischemic cortex, the level of SMS1 transcripts is decreased, overview | Rattus norvegicus | - |
neuron | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | SMS1 is a key enzyme in the sphingomyelin cycle, metabolites of the cycle play an important role in neuronal death after ischemia, mechanism underlying cerebral ischemia, overview | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SMS1 | - |
Rattus norvegicus |
sphingomyelin synthase 1 | - |
Rattus norvegicus |