Any feedback?
Literature summary for 2.7.8.2 extracted from
- Ceramide phosphoethanolamine biosynthesis in Drosophila is mediated by a unique ethanolamine phosphotransferase in the Golgi lumen (2013), J. Biol. Chem., 288, 11520-11530.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene CG7149, DNA and amino acid sequence determination and analysis, phylogenetic analysis, recombinant expression from vector mammalian expression vector pcDNA3.1/V5-His-TOPO in HeLa cells and in Drosophila S2 cells | Drosophila melanogaster |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| Golgi apparatus | - |
Drosophila melanogaster | 5794 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDP-choline + 1,2-diacyl-sn-glycerol | Drosophila melanogaster | - |
CMP + a phosphatidylcholine | - |
r |  |
| CDP-ethanolamine + 1,2-diacyl-sn-glycerol | Drosophila melanogaster | - |
CMP + a phosphatidylethanolamine | - |
r | |
| additional information | Drosophila melanogaster | the enzyme has dual specificity for both CDP-choline and CDP-ethanolamine, EC 2.7.8.1 | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Drosophila melanogaster | Q8T0S3 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDP-choline + 1,2-diacyl-sn-glycerol | - |
Drosophila melanogaster | CMP + a phosphatidylcholine | - |
r | |
| CDP-ethanolamine + 1,2-diacyl-sn-glycerol | - |
Drosophila melanogaster | CMP + a phosphatidylethanolamine | - |
r | |
| additional information | the enzyme has dual specificity for both CDP-choline and CDP-ethanolamine, EC 2.7.8.1 | Drosophila melanogaster | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CEPT | - |
Drosophila melanogaster |
| CG7149 | - |
Drosophila melanogaster |
| CG7149, isoform A | UniProt | Drosophila melanogaster |
| dCCS3 | - |
Drosophila melanogaster |
| diacylglycerol cholinephosphotransferase | - |
Drosophila melanogaster |
General Information
| General Information | Comment | Organism |
|---|---|---|
| evolution | the enzyme belongs to the CEPT subfamily | Drosophila melanogaster |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
