Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.8.2 extracted from

  • Roy, S.S.; Mukherjee, S.; Mukhopadhyay, S.; Das, S.K.
    Differential effect of cadmium on cholinephosphotransferase activity in normal and cancerous human mammary epithelial cell lines (2004), Mol. Cancer Ther., 3, 199-204.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens increase in cholinephosphotransferase gene expression with cadmium in all cell lines, significant increase in 11-9-1-4 cells and MCF-12F cells. Cell lines MCF-12F, MCF-7, BT-549 and 11-9-1-4 show mutations in their nucleotide sequence as the result of cadmium treatment. The effect of cadmium is highest in MCF-12F cell line that shows a total of six mutations ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
11-9-1-4 cell
-
Homo sapiens
-
BT-549 cell
-
Homo sapiens
-
epithelial cell line normal: MCF-12A and MCF-12F and cancerous: MCF-7, BT-549 and 11-9-1-4 Homo sapiens
-
MCF-12A cell
-
Homo sapiens
-
MCF-12F cell
-
Homo sapiens
-
MCF-7 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information increase in cholinephosphotransferase gene expression with cadmium in all cell lines, significant increase in 11-9-1-4 cells and MCF-12F cells. Cell lines MCF-12F, MCF-7, BT-549 and 11-9-1-4 show mutations in their nucleotide sequence as the result of cadmium treatment. The effect of cadmium is highest in MCF-12F cell line that shows a total of six mutations Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
cholinephosphotransferase
-
Homo sapiens
CPT
-
Homo sapiens