Any feedback?
Literature summary for 2.7.8.2 extracted from
- Hamster liver cholinephosphotransferase and ethanolaminephosphotransferase are separate enzymes (1989), Biochem. Cell Biol., 67, 680-686.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Phospholipids | phosphatidylcholine, phosphatidylethanolamine or lysophosphatidylethanolamine activates, lysophosphatidylcholine inhibits | Mesocricetus auratus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| CHAPS | - |
Mesocricetus auratus | |
| CHAPSO | - |
Mesocricetus auratus | |
| n-octylglucoside | - |
Mesocricetus auratus | |
| Phospholipids | phosphatidylcholine, phosphatidylethanolamine or lysophosphatidylethanolamine activates, lysophosphatidylcholine inhibits | Mesocricetus auratus | |
| Triton X-100 | X-200 | Mesocricetus auratus | |
| Tween-20 | - |
Mesocricetus auratus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Mesocricetus auratus | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | absolute requirement for Mg2+ or Mn2+ | Mesocricetus auratus | |
| Mg2+ | maximal activation at 10 mM | Mesocricetus auratus | |
| Mn2+ | absolute requirement for Mg2+ or Mn2+ | Mesocricetus auratus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDP-choline + sn-1,2-diacylglycerol | Mesocricetus auratus | final reaction in synthesis of phosphatidylcholine | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mesocricetus auratus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Mesocricetus auratus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Mesocricetus auratus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDP-choline + 1,2-diacylglycerol | - |
Mesocricetus auratus | CMP + a phosphatidylcholine | - |
? | |
| CDP-choline + sn-1,2-diacylglycerol | final reaction in synthesis of phosphatidylcholine | Mesocricetus auratus | ? | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 55 | - |
1 min, 90% loss of activity, whole microsomes, less than 60% loss of activity, partially purified enzyme | Mesocricetus auratus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
