Literature summary for 2.7.8.15 extracted from

Mendelsohn, R.D.; Helmerhorst, E.J.; Cipollo, J.F.; Kukuruzinska, M.A.
A hypomorphic allele of the first N-glycosylation gene, ALG7, causes mitochondrial defects in yeast (2005), Biochim. Biophys. Acta, 1723, 33-44.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Saccharomyces cerevisiae	alg7 mutants show diminished activity of GPT, reduced steady-state levels of lipid-linked oligosaccharides and hypoglycosylated carboxypeptidase Y. Mutants also lack mitochondrial DNA including the genes that encode the components of the respiratory machinery	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	alg7 mutants show diminished activity of GPT, reduced steady-state levels of lipid-linked oligosaccharides and hypoglycosylated carboxypeptidase Y. Mutants also lack mitochondrial DNA including the genes that encode the components of the respiratory machinery	Saccharomyces cerevisiae	?	-	?

Synonyms

Synonyms	Comment	Organism
Dol-P dependent GlcNAc-1-P transferase	enzyme is encoded by ALG7	Saccharomyces cerevisiae
GPT	-	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)