Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cardiolipin | stimulates activity of enzyme in endoplasmic membrane vesicles, due to better solubilization of the dolichol phosphate | Rattus norvegicus | |
monogalactosyldiglyceride | stimulates activity of enzyme in endoplasmic membrane vesicles | Rattus norvegicus | |
phosphatidylethanolamine | stimulates activity of enzyme in endoplasmic membrane vesicles | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Triton X-100 | substrate protects from inhibition | Rattus norvegicus | |
tunicamycin | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Km-value for dolichyl phosphate: 0.005 mg/0.1 ml | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Rattus norvegicus | 5783 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate | - |
Rattus norvegicus | UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
40 | - |
with 0.5% Triton X-100 in the assay mixture | Rattus norvegicus |
60 | - |
with either dioleoylphosphatidylethanolamine or cardiolipin in the assay mixture | Rattus norvegicus |