Any feedback?
Literature summary for 2.7.8.14 extracted from
- The synthesis of polyribitol phosphate. I. Purification of polyribitol phosphate polymerase and lipoteichoic acid carrier (1974), J. Biol. Chem., 249, 2684-2689.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| cardiolipin | stimulates 6fold at 0.36 mM | Staphylococcus aureus |  |
| lipoteichoic acid | required as carrier | Staphylococcus aureus | |
| phosphatidylcholine | stimulates 2.7fold 0.36 mM | Staphylococcus aureus | |
| phosphatidylethanolamine | stimulates 5fold 0.36 mM | Staphylococcus aureus | |
| phosphatidylglycerol | stimulates 4fold 0.36 mM | Staphylococcus aureus | |
| Phospholipid | required | Staphylococcus aureus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-hydroxymercuribenzoate | inhibition at 0.4 mM, can be reversed by 2-mercaptoethanol | Staphylococcus aureus | |
| CDPglycerol | weak | Staphylococcus aureus | |
| CMP | - |
Staphylococcus aureus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDPribitol + (ribitol phosphate)n | Staphylococcus aureus | - |
CMP + (ribitol phosphate)n+1 | - |
? | |
| CDPribitol + (ribitol phosphate)n | Staphylococcus aureus H | - |
CMP + (ribitol phosphate)n+1 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Staphylococcus aureus | - |
H | - |
| Staphylococcus aureus H | - |
H | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| 400fold | Staphylococcus aureus |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0035 | - |
- |
Staphylococcus aureus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDPribitol + (ribitol phosphate)n | - |
Staphylococcus aureus | CMP + (ribitol phosphate)n+1 | - |
? | |
| CDPribitol + (ribitol phosphate)n | - |
Staphylococcus aureus H | CMP + (ribitol phosphate)n+1 | - |
? | |
| CDPribitol + lipoteichoic acid | - |
Staphylococcus aureus | lipoteichoic acid-(P-ribitol)n + CMP | - |
? | |
| CDPribitol + lipoteichoic acid | - |
Staphylococcus aureus H | lipoteichoic acid-(P-ribitol)n + CMP | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
24 h, very stable | Staphylococcus aureus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
