Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.8.13 extracted from

  • Pless, D.D.; Neuhaus, F.C.
    Initial membrane reaction in peptidoglycan synthesis. Lipid dependence of phospho-n-acetylmuramyl-pentapeptide translocase (exchange reaction) (1973), J. Biol. Chem., 248, 1568-1576.
    View publication on PubMed
Search for more literature for 2.7.8.13

Activating Compound

Activating Compound Comment Organism Structure
undecaprenyl phosphate stimulates exchange reaction Staphylococcus aureus
Undecaprenyl-diphosphate-MurNAc-pentapeptide stimulates exchange reaction Staphylococcus aureus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Staphylococcus aureus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-NAc-muramoyl-pentapeptide + acceptor Staphylococcus aureus initial stage in peptidoglycan synthesis, key role in selecting analogs of UDP-MurNAc-Ala-gammaDGlu-Lys-DAla-DAla, membrane associated reaction of cell wall biosynthesis UMP + acceptor-phospho-NAc-muramoyl-pentapeptide
-
 r
UDP-NAc-muramoyl-pentapeptide + acceptor Staphylococcus aureus Copenhagen initial stage in peptidoglycan synthesis, key role in selecting analogs of UDP-MurNAc-Ala-gammaDGlu-Lys-DAla-DAla, membrane associated reaction of cell wall biosynthesis UMP + acceptor-phospho-NAc-muramoyl-pentapeptide
-
 r

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus
-
 Copenhagen
-
Staphylococcus aureus Copenhagen
-
 Copenhagen
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-MurNAc-pentapeptide + undecaprenoid-1-ol-phosphate
-
 Staphylococcus aureus lipid-P-P-MurNAc-pentapeptide + UMP
-
 r
UDP-MurNAc-pentapeptide + undecaprenoid-1-ol-phosphate
-
 Staphylococcus aureus Copenhagen lipid-P-P-MurNAc-pentapeptide + UMP
-
 r
UDP-NAc-muramoyl-pentapeptide + acceptor
-
 Staphylococcus aureus UMP + acceptor-phospho-NAc-muramoyl-pentapeptide
-
 r
UDP-NAc-muramoyl-pentapeptide + acceptor initial stage in peptidoglycan synthesis, key role in selecting analogs of UDP-MurNAc-Ala-gammaDGlu-Lys-DAla-DAla, membrane associated reaction of cell wall biosynthesis Staphylococcus aureus UMP + acceptor-phospho-NAc-muramoyl-pentapeptide
-
 r
UDP-NAc-muramoyl-pentapeptide + acceptor
-
 Staphylococcus aureus Copenhagen UMP + acceptor-phospho-NAc-muramoyl-pentapeptide
-
 r
UDP-NAc-muramoyl-pentapeptide + acceptor initial stage in peptidoglycan synthesis, key role in selecting analogs of UDP-MurNAc-Ala-gammaDGlu-Lys-DAla-DAla, membrane associated reaction of cell wall biosynthesis Staphylococcus aureus Copenhagen UMP + acceptor-phospho-NAc-muramoyl-pentapeptide
-
 r