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Literature summary for 2.7.8.11 extracted from

  • Cubitt, A.B.; Gershengorn, M.C.
    Characterization of a salt-extractable phosphatidylinositol synthase from rat pituitary-tumour membranes (1989), Biochem. J., 257, 639-644.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.8.11

Inhibitors

Inhibitors Comment Organism Structure
Ca2+
-
 Rattus norvegicus
myo-inositol substrate inhibition above 1 mM Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.06
-
 myo-inositol pH 7.5, 37°C Rattus norvegicus
0.21
-
 CDP-diacylglycerol pH 7.5, 37°C Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Rattus norvegicus 5783
-
membrane
-
 Rattus norvegicus 16020
-
plasma membrane
-
 Rattus norvegicus 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Rattus norvegicus
Mn2+
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CDP-diacylglycerol + myo-inositol Rattus norvegicus
-
 CMP + phosphatidyl-1D-myo-inositol
-
 r

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 rat
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
pituitary gland tumor cell GH3 tumour Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.00025
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CDP-diacylglycerol + myo-inositol
-
 Rattus norvegicus CMP + phosphatidyl-1D-myo-inositol
-
 r

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7 7.5
-
 Rattus norvegicus