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Literature summary for 2.7.8.1 extracted from

  • Liteplo, R.G.; Sribney, M.
    Inhibition of rat liver CDPethanolamine: 1,2-diacylglycerol ethanolamine-phosphotransferase activity by ATP and pantothenic acid derivatives (1977), Can. J. Biochem., 55, 1049-1056.
    View publication on PubMed
Search for more literature for 2.7.8.1

Inhibitors

Inhibitors Comment Organism Structure
ATP plus pantetheine: inhibition of Mn2+- and Mg2+-activated enzyme, plus CoA: inhibition of Mn2+-activated enzyme, slight stimulation of Mg2+-activated enzyme, ATP alone: inhibition of Mg2+- and Mn2+-activated enzyme Rattus norvegicus
Ca2+ Mg2+- or Mn2+-activated enzyme Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ Mg2+ at 20 mM or Mn2+ at 1 mM required for optimum activity Rattus norvegicus
Mn2+ Mg2+ at 20 mM or Mn2+ at 1 mM required for optimum activity Rattus norvegicus
Mn2+ much more effective than Mg2+ Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CDP-ethanolamine + 1,2-diacylglycerol
-
 Rattus norvegicus CMP + a phosphatidylethanolamine
-
 ?