Cloned (Comment) | Organism |
---|---|
DNA sequence determination and analysis of several IS1341-type transposases (tnpB genes), existence of sense overlapping transcripts (sotRNAs) for all IS1341-type transposases in Halobacterium salinarum strain NRC-1, condition-dependent differential regulation between sotRNAs and their cognate genes. Identification of a UUCA tetraloop motif that is present in other archaea (ncRNA family HgcC) and in a Halobacterium salinarum intergenic ncRNA derived from a palindrome associated transposable elements (PATE). Overexpression of one sotRNA and the PATE-derived RNA harboring the tetraloop motif improves Halobacterium salinarum growth, indicating that these ncRNAs are functional. IS1341-type transposase genes harbor the right end (RE) of the IS element, which may explain the sotRNA motifs found as a retained structure formed at DNA level, also stable at RNA level, i.e. the RE-like tetraloop | Halobacterium salinarum |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | - |
Halobacterium salinarum | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Halobacterium salinarum | - |
- |
- |
Halobacterium salinarum NRC 1 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
IS1341-type transposase | - |
Halobacterium salinarum |
General Information | Comment | Organism |
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evolution | the IS1341-type transposase is part of the widespread IS200/605 family, the most ancient family in the archaeal domain of life. Presence in Halobacterium salinarum strain NRC-1 of a probable sotRNA in a nonfunctional IS1341-type transposase gene, a truncated small 120 bp long pseudogene identical to OE5220R, suggests that sotRNA presence may somehow be the reason why these defective elements have not been lost from the genomes | Halobacterium salinarum |