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Literature summary for 2.7.7.96 extracted from

  • Yu, H.N.; Song, E.K.; Yoo, S.M.; Lee, Y.R.; Han, M.K.; Yim, C.Y.; Kwak, J.Y.; Kim, J.S.
    Activation of NUDT5, an ADP-ribose pyrophosphatase, by nitric oxide-mediated ADP-ribosylation (2007), Biochem. Biophys. Res. Commun., 354, 764-768.
    View publication on PubMed
Search for more literature for 2.7.7.96

Activating Compound

Activating Compound Comment Organism Structure
nitric oxide nitric oxide stimulates nonenzymatic ADP-ribosylation of NUDT5 at cysteine residues using ADP-ribose and consequently activates its enzyme activity Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
N(G)-nitro-L-arginine methyl ester
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000
-
 x * 40000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + D-ribose 5-phosphate Homo sapiens
-
 diphosphate + ADP-D-ribose
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
J-774 cell
-
 Homo sapiens
-
macrophage
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-ribose 5-phosphate
-
 Homo sapiens diphosphate + ADP-D-ribose
-
 ?

Subunits

Subunits Comment Organism
? x * 40000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
ADP-ribose pyrophosphatase
-
 Homo sapiens
ADPRase
-
 Homo sapiens
NUDT5
-
 Homo sapiens