Literature summary for 2.7.7.92 extracted from

Tiralongo, J.; Fujita, A.; Sato, C.; Kitajima, K.; Lehmann, F.; Oschlies, M.; Gerardy-Schahn, R.; Muenster-Kuehnel, A.K.
The rainbow trout CMP-sialic acid synthetase utilises a nuclear localization signal different from that identified in the mouse enzyme (2007), Glycobiology, 17, 945-954.

Search for more literature for 2.7.7.92

Cloned(Commentary)

Cloned (Comment)	Organism
-	Oncorhynchus mykiss

Protein Variants

Protein Variants	Comment	Organism
additional information	construction of mutants lacking individual basic amino acids in the N-terminus, disruption of putative nuclear localization signal	Oncorhynchus mykiss

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
nucleus	the crucial nuclear localization signal in the fish enzyme is bipartite and the functionality depends on a free N-terminus. Nuclear transport and enzymatic activity are independent functions. The sequence K5K6R7 is sufficient to direct GFP to the nucleus, and is necessary for the nuclear import of the CMP-Sia-synthetase in fish cells	Oncorhynchus mykiss	5634	-

Organism

Organism	UniProt	Comment	Textmining
Oncorhynchus mykiss	Q90WG6	cf. EC 2.7.7.43	-

Synonyms

Synonyms	Comment	Organism
CMP-Sia synthetase	-	Oncorhynchus mykiss

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)