Application | Comment | Organism |
---|---|---|
medicine | isoforms OAS1 p46 and OAS3 p100 mediate the RNase L-dependent antiviral activity against hepatitis C virus. The expression of isoform p46 shows a notable inhibition for the protein expression from HCV JFH-1 in an RNase L-dependent manner, whereas no inhibitory effect is produced by the p42, p48 or p52 isoforms of OAS1 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P00973 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | OAS1 and OAS3 transcripts are constitutively expressed | Homo sapiens | - |
Huh-7 cell | OAS1 and OAS3 transcripts are constitutively expressed | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
OAS1 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | expression is significantly induced following interferon treatment | up |