Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aquifex aeolicus | O67911 | cf. EC 2.7.7.19 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | in Aquifex aeolicus, 3'-terminal CCA (CCA-3' at positions 74-76) of tRNA is synthesized by CC-adding and A-adding enzymes collaboratively. CC addition onto tRNA is catalyzed by poly A polymerase. After C74 addition in an enclosed active pocket and diphosphate release, the tRNA translocates and rotates relative to the enzyme, and C75 addition occurs in the same active pocket as C74 addition. At both the C74-adding and C75-adding stages, CTP is selected by Watson-Crick-like hydrogen bonds between the cytosine of CTP and conserved Asp and Arg residues in the pocket. After C74C75 addition and diphosphate release, the tRNA translocates further and drops off the enzyme | Aquifex aeolicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AAS | - |
Aquifex aeolicus |
CC-adding enzyme | - |
Aquifex aeolicus |
pcnB2 | - |
Aquifex aeolicus |
pcnB2 aq_2158 | - |
Aquifex aeolicus |
poly A polymerase | - |
Aquifex aeolicus |