Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Human alphaherpesvirus 1 | comparing RNA primer-templates and DNA primer templates of identical sequence show that herpes polymerase greatly prefers to elongate the DNA primer by 650-26000fold, thus accounting for the extremely low efficiency with which herpes polymerase elongates primase-synthesized primers | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Human alphaherpesvirus 1 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
deoxynucleoside triphosphate + DNAn | - |
Homo sapiens | diphosphate + DNAn+1 | - |
? | |
deoxynucleoside triphosphate + DNAn | herpes polymerase only elongates primase-synthesized primers at least 8 nucleotides long | Human alphaherpesvirus 1 | diphosphate + DNAn+1 | - |
? | |
additional information | comparing RNA primer-templates and DNA primer templates of identical sequence show that herpes polymerase greatly prefers to elongate the DNA primer by 650-26000fold, thus accounting for the extremely low efficiency with which herpes polymerase elongates primase-synthesized primers | Human alphaherpesvirus 1 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DNA polymerase | - |
Human alphaherpesvirus 1 |
DNA polymerase alpha | - |
Homo sapiens |
pol alpha | - |
Homo sapiens |
UL30/UL42 | - |
Human alphaherpesvirus 1 |
General Information | Comment | Organism |
---|---|---|
physiological function | polymerase alpha (p70-p180 or p49-p58-p70-p180 complex) extends herpes primase-synthesized RNA primers much more efficiently than herpes polymerase | Homo sapiens |