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Literature summary for 2.7.7.67 extracted from

  • Jain, S.; Caforio, A.; Fodran, P.; Lolkema, J.S.; Minnaard, A.J.; Driessen, A.J.
    Identification of CDP-archaeol synthase, a missing link of ether lipid biosynthesis in Archaea (2014), Chem. Biol., 21, 1392-1401.
    View publication on PubMed
Search for more literature for 2.7.7.67

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Archaeoglobus fulgidus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.12
-
 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate pH 7.5, 65°C Archaeoglobus fulgidus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Archaeoglobus fulgidus 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Archaeoglobus fulgidus

Organism

Organism UniProt Comment Textmining
Archaeoglobus fulgidus O28534
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CTP + 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
-
 Archaeoglobus fulgidus diphosphate + CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
-
 ?
dCTP + 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
-
 Archaeoglobus fulgidus diphosphate + dCDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
-
 ?
additional information no substrates: ATP, GTP, TTP Archaeoglobus fulgidus ?
-
 ?

Synonyms

Synonyms Comment Organism
AF_1740
-
 Archaeoglobus fulgidus
CarS
-
 Archaeoglobus fulgidus
CDP-archaeol synthase
-
 Archaeoglobus fulgidus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.55
-
 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate pH 7.5, 65°C Archaeoglobus fulgidus