Crystallization (Comment) | Organism |
---|---|
to 2.9 A resolution. A peptide loop extending from the GAF domain occupies the conserved inhibition site, thereby largely relieving the product-inhibition effect. A large hydrophobic pocket is observed in the GAF domain | Pseudomonas aeruginosa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | Q9I072 | - |
- |
Pseudomonas aeruginosa DSM 22644 | Q9I072 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 GTP | - |
Pseudomonas aeruginosa | 2 diphosphate + cyclic di-3',5'-guanylate | - |
? | |
2 GTP | - |
Pseudomonas aeruginosa DSM 22644 | 2 diphosphate + cyclic di-3',5'-guanylate | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | full-length Dcsbis protein contains an N-terminal GAF domain and a C-terminal GGDEF domain | Pseudomonas aeruginosa |
Synonyms | Comment | Organism |
---|---|---|
Dcsbis | - |
Pseudomonas aeruginosa |
PA2771 | - |
Pseudomonas aeruginosa |
General Information | Comment | Organism |
---|---|---|
physiological function | Dcsbis tightly coordinates cell motility without markedly affecting biofilm formation and is a diguanylate cyclase with a catalytic activity much higher than those of many other diguanylate cyclases | Pseudomonas aeruginosa |