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Literature summary for 2.7.7.6 extracted from

  • Mohamed, M.R.; Niles, E.G.
    Interaction between nucleoside triphosphate phosphohydrolase I and the H4L subunit of the viral RNA polymerase is required for vaccinia virus early gene transcript release (2000), J. Biol. Chem., 275, 25798-25804.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nucleoside triphosphate + RNAn Vaccinia virus nucleoside triphosphate phosphohydrolase I binds to the H4L subunit of virion RNA polymerase. These observation provides an explanation that UUUUUNU-dependent transcription termination is restricted to early genes, whose transcription is catalyzed by the H4L-containing virion RNA polymerase diphosphate + RNAn+1
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?
nucleoside triphosphate + RNAn Vaccinia virus WR nucleoside triphosphate phosphohydrolase I binds to the H4L subunit of virion RNA polymerase. These observation provides an explanation that UUUUUNU-dependent transcription termination is restricted to early genes, whose transcription is catalyzed by the H4L-containing virion RNA polymerase diphosphate + RNAn+1
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?

Organism

Organism UniProt Comment Textmining
Vaccinia virus
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Vaccinia virus WR
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nucleoside triphosphate + RNAn the enzyme requires DNA as template Vaccinia virus diphosphate + RNAn+1
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?
nucleoside triphosphate + RNAn nucleoside triphosphate phosphohydrolase I binds to the H4L subunit of virion RNA polymerase. These observation provides an explanation that UUUUUNU-dependent transcription termination is restricted to early genes, whose transcription is catalyzed by the H4L-containing virion RNA polymerase Vaccinia virus diphosphate + RNAn+1
-
?
nucleoside triphosphate + RNAn the enzyme requires DNA as template Vaccinia virus WR diphosphate + RNAn+1
-
?
nucleoside triphosphate + RNAn nucleoside triphosphate phosphohydrolase I binds to the H4L subunit of virion RNA polymerase. These observation provides an explanation that UUUUUNU-dependent transcription termination is restricted to early genes, whose transcription is catalyzed by the H4L-containing virion RNA polymerase Vaccinia virus WR diphosphate + RNAn+1
-
?