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Literature summary for 2.7.7.6 extracted from

  • Sadhukhan, P.K.; Cgakraborty, A.K.; Dasgupta, A.; Majumder, H.K.
    Chromatographic separation of DNA dependent RNA polymerases and molecular properties of RNA polymerase II from a Leishmania spp (1997), Mol. Cell. Biochem., 171, 105-114.
    View publication on PubMed
Search for more literature for 2.7.7.6

Inhibitors

Inhibitors Comment Organism Structure
alpha-amanithin
-
 Leishmania sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
480000
-
 glycerol gradient centrifugation Leishmania sp.
562000
-
 non-denaturing gel filtration Leishmania sp.
583000
-
 gel filtration Leishmania sp.

Organism

Organism UniProt Comment Textmining
Leishmania sp.
-
-
-
Leishmania sp. UR6
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
promastigote
-
 Leishmania sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nucleoside triphosphate + RNAn the enzyme requires DNA as template Leishmania sp. diphosphate + RNAn+1
-
 ?
nucleoside triphosphate + RNAn the enzyme requires DNA as template Leishmania sp. UR6 diphosphate + RNAn+1
-
 ?

Subunits

Subunits Comment Organism
? the most probably subunit structure for the enzyme is the following: 154000 + 104000 + 77000 + 64000 + 52000 + 48000 + 46000 + 45000 + 39000 Leishmania sp.