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BRENDA support

Literature summary for 2.7.7.6 extracted from

  • Weaver, R.F.; Blatti, S.P.; Rutter, W.J.
    Molecular structures of DNA-dependent RNA polymerases (II) from calf thymus and rat liver (1971), Proc. Natl. Acad. Sci. USA, 68, 2994-2999.
    View publication on PubMedView publication on EuropePMC

General Stability

General Stability Organism
nucleolar enzyme appears to be less stable than the nucleoplasmic enzyme, particularly in the presence of salt Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rattus norvegicus
-
Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-
thymus
-
Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.05
-
-
Rattus norvegicus
0.05
-
-
Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nucleoside triphosphate + RNAn the enzyme requires DNA as template Rattus norvegicus diphosphate + RNAn+1
-
?
nucleoside triphosphate + RNAn the enzyme requires DNA as template Bos taurus diphosphate + RNAn+1
-
?