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Literature summary for 2.7.7.56 extracted from

  • Basturea, G.N.; Zundel, M.A.; Deutscher, M.P.
    Degradation of ribosomal RNA during starvation: comparison to quality control during steady-state growth and a role for RNase PH (2011), RNA, 17, 338-345.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Escherichia coli for 16S rRNA degradation during glucose starvation, leading to slow cell growth, begins with shortening of its 3' end in a reaction catalyzed by RNase PH ?
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?
additional information Escherichia coli MG1655 for 16S rRNA degradation during glucose starvation, leading to slow cell growth, begins with shortening of its 3' end in a reaction catalyzed by RNase PH ?
-
?
tRNAn+1 + phosphate Escherichia coli degradation of 16S rRNA substrate 3' end tRNAn + a nucleoside diphosphate
-
?
tRNAn+1 + phosphate Escherichia coli MG1655 degradation of 16S rRNA substrate 3' end tRNAn + a nucleoside diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
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-
-
Escherichia coli MG1655
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information for 16S rRNA degradation during glucose starvation, leading to slow cell growth, begins with shortening of its 3' end in a reaction catalyzed by RNase PH Escherichia coli ?
-
?
additional information for 16S rRNA degradation during glucose starvation, leading to slow cell growth, begins with shortening of its 3' end in a reaction catalyzed by RNase PH Escherichia coli MG1655 ?
-
?
tRNAn+1 + phosphate degradation of 16S rRNA substrate 3' end Escherichia coli tRNAn + a nucleoside diphosphate
-
?
tRNAn+1 + phosphate 16S rRNA substrate Escherichia coli tRNAn + a nucleoside diphosphate
-
?
tRNAn+1 + phosphate degradation of 16S rRNA substrate 3' end Escherichia coli MG1655 tRNAn + a nucleoside diphosphate
-
?
tRNAn+1 + phosphate 16S rRNA substrate Escherichia coli MG1655 tRNAn + a nucleoside diphosphate
-
?

Synonyms

Synonyms Comment Organism
RNase PH
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Escherichia coli

General Information

General Information Comment Organism
malfunction in the absence of RNase PH, there is no 3' end trimming of 16S rRNA and no accumulation of rRNA fragments, and total RNA degradation is greatly reduced. In contrast, the degradation pattern in quality control remains unchanged when RNase PH is absent Escherichia coli
metabolism RNase PH is involved in the starvation rRNA degradative pathway Escherichia coli
physiological function the enzym eis required for the pathway of ribosomal RNA degradation during glucose starvation, not for the pathway of ribosomal RNA degradation in quality control during steady-state growth Escherichia coli