Any feedback?
Literature summary for 2.7.7.49 extracted from
- The many faces of telomerase: emerging extratelomeric effects (2008), Bioessays, 30, 728-732.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Homo sapiens | 5829 | - |
| mitochondrion | - |
Homo sapiens | 5739 | - |
| nucleus | - |
Homo sapiens | 5634 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | telomerase function comprises lengthening of telomeres, enhancement of DNA repair, promotion of cell growth, modulation of mitochondrial functions under oxidative stress, inhibition of apoptosis, promotion of stem cell proliferation, suppression of DNA damage checkpoints | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| deoxynucleoside triphosphate + DNAn | - |
Homo sapiens | diphosphate + DNAn+1 | - |
? | |
| additional information | telomerase function comprises lengthening of telomeres, enhancement of DNA repair, promotion of cell growth, modulation of mitochondrial functions under oxidative stress, inhibition of apoptosis, promotion of stem cell proliferation, suppression of DNA damage checkpoints | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| reverse transcriptase | - |
Homo sapiens |
| telomerase | telomerase lengthens telomeres by its reverse transcriptase activity | Homo sapiens |
| TERT | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
