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Literature summary for 2.7.7.49 extracted from

  • Shandilya, H.; Griffiths, K.; Flynn, E.K.; Astatke, M.; Shih, P.J.; Lee, J.E.; Gerard, G.F.; Gibbs, M.D.; Bergquist, P.L.
    Thermophilic bacterial DNA polymerases with reverse-transcriptase activity (2004), Extremophiles, 8, 243-251.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ DNA polymerase shows significant reverse-transcriptase activity in presence of Mg2+ [Bacillus] caldolyticus
Mg2+ DNA polymerase shows significant reverse-transcriptase activity in presence of Mg2+ Thermoclostridium stercorarium
Mg2+ DNA polymerase shows significant reverse-transcriptase activity in presence of Mg2+ [Caldibacillus] cellulovorans

Organism

Organism UniProt Comment Textmining
Thermoclostridium stercorarium
-
-
-
[Bacillus] caldolyticus
-
EA1
-
[Bacillus] caldolyticus EA1
-
EA1
-
[Caldibacillus] cellulovorans
-
CompA.2
-
[Caldibacillus] cellulovorans CompA.2
-
CompA.2
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxynucleoside triphosphate + DNAn DNA polymerase shows significant reverse-transcriptase activity in presence of Mg2+ [Bacillus] caldolyticus diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn DNA polymerase shows significant reverse-transcriptase activity in presence of Mg2+ Thermoclostridium stercorarium diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn DNA polymerase shows significant reverse-transcriptase activity in presence of Mg2+ [Caldibacillus] cellulovorans diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn DNA polymerase shows significant reverse-transcriptase activity in presence of Mg2+ [Bacillus] caldolyticus EA1 diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn DNA polymerase shows significant reverse-transcriptase activity in presence of Mg2+ [Caldibacillus] cellulovorans CompA.2 diphosphate + DNAn+1
-
?

Synonyms

Synonyms Comment Organism
More DNA polymerase with reverse-transcriptase activity [Caldibacillus] cellulovorans