Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.7.48 extracted from

  • Ahn, D.G.; Choi, J.K.; Taylor, D.R.; Oh, J.W.
    Biochemical characterization of a recombinant SARS coronavirus nsp12 RNA-dependent RNA polymerase capable of copying viral RNA templates (2012), Arch. Virol., 157, 2095-2104.
    View publication on PubMed
Search for more literature for 2.7.7.48

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Severe acute respiratory syndrome-related coronavirus

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ strictly dependent on Mn2+ Severe acute respiratory syndrome-related coronavirus

Organism

Organism UniProt Comment Textmining
Severe acute respiratory syndrome-related coronavirus P0C6X7 replicase polyprotein 1ab
-

Purification (Commentary)

Purification (Comment) Organism
recombinant protein Severe acute respiratory syndrome-related coronavirus

Storage Stability

Storage Stability Organism
-80°C, stable for at least 3 months Severe acute respiratory syndrome-related coronavirus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme shows both primer-dependent and primer-independent RNA synthesis activities using homopolymeric RNA templates. It preferentially copies homopolymeric pyrimidine RNA templates in the absence of an added oligonucleotide primer and is also able to initiate de novo RNA synthesis from the 3'-ends of both the plus- and minus-strand genome of human SARS coronavirus, using the 3'-terminal 36- and 37-nt RNA, respectively Severe acute respiratory syndrome-related coronavirus ?
-
 ?

Synonyms

Synonyms Comment Organism
nonstructural protein 12
-
 Severe acute respiratory syndrome-related coronavirus
nsp12
-
 Severe acute respiratory syndrome-related coronavirus
RDRP
-
 Severe acute respiratory syndrome-related coronavirus