Any feedback?
Literature summary for 2.7.7.48 extracted from
- A Pol V-mediated silencing, independent of RNA-directed DNA methylation, applies to 5S rDNA (2009), PLoS Genet., 5, e1000690.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene dr2, RT-PCR expression analysis | Arabidopsis thaliana |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | construction of dr2 knockout mutant plants, rdr2-1, showing reduced asymmetric 5S rDNA methylation at chromosomes 4 and 5 compared to the wild-type enzyme | Arabidopsis thaliana |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | - |
ecotype Col-0, gene dr2 | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| RDR2 | - |
Arabidopsis thaliana |
| RNA-Dependent RNA Polymerase 2 | - |
Arabidopsis thaliana |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme is required for the RNA-directed DNA methylation, dedicated to the methylation of target sequences, which include transposable elements, regulatory regions of several protein-coding genes, and 5S rRNA-encoding DNA arrays. Pol IV, RDR2, DRM2, and Pol V, actors of the RdDM, are required to maintain a transcriptional silencing of 5S RNA genes at chromosomes 4 and 5, regulation, overview | Arabidopsis thaliana |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
