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BRENDA support

Literature summary for 2.7.7.48 extracted from

  • Brandl, M.; Wu, X.; Holper, M.; Hong, L.; Jia, Z.; Birudaraj, R.; Reddy, M.; Alfredson, T.; Tran, T.; Larrabee, S.; Hadig, X.; Sarma, K.; Washington, C.; Hill, G.; Smith, D.B.
    Physicochemical properties of the nucleoside prodrug R1626 leading to high oral bioavailability (2008), Drug Dev. Ind. Pharm., 34, 683-691.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
4'-azidocytidine R-1479, potent and highly selective inhibitor Hepacivirus C

Organism

Organism UniProt Comment Textmining
Hepacivirus C
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nucleoside triphosphate + RNAn
-
Hepacivirus C diphosphate + RNAn+1
-
?

Synonyms

Synonyms Comment Organism
NS5b-directed RNA polymerase
-
Hepacivirus C